Texas reports what may be the first U.S. death from monkeypox

The virus is primarily spreading through sexual contact among gay and bisexual men, according to the CDC. About 94% of confirmed cases were associated with sex and nearly all of the patients are men who have sex with men, Demetre Daskalakis, deputy head of the White House monkeypox response team, told reporters Friday.

The outbreak in the U.S. is disproportionately affecting Black and Hispanic men.  About 30% of monkeypox patients are white, 32% are Hispanic and 33% are Black, according to CDC data. Whites make up about 59% of the U.S. population while Hispanics and Blacks account for 19% and 13%, respectively.

CDC Director Dr. Rochelle Walensky on Friday said health officials are cautiously optimistic the spread of the virus may be slowing as new cases fall in major cities.

“We’re watching this with cautious optimism, and really hopeful that many of our harm-reduction messages and our vaccines are getting out there and working,” Walensky told reporters Friday.

The U.S. is hoping to contain the outbreak by administering vaccines, expanding testing, distributing antiviral treatments, and educating gay and bisexual men about the virus.

The federal government has distributed 1.5 million doses of the monkeypox vaccine so far. More than 3 million doses should be available to states and local jurisdictions when the latest distribution round is complete, according Dawn O’Connell, head of the office responsible for the national stockpile at the Health and Human Services Department.

The monkeypox vaccine, called Jynneos, is administered in two doses 28 days apart. It is the only vaccine approved by the Food and Drug Administration in the U.S. for monkeypox. Jynneos is manufactured by Bavarian Nordic, a biotech company based in Denmark.

To increase the limited supply, the FDA has authorized a different method to administer the vaccine. The vaccine is now being given through intradermal injection for adults, or between the layers of the skin. This method uses a lower volume dosage which allows health-care providers to extract five doses from each vial.

There is no data on the real-world efficacy of the vaccine in the current outbreak, according to the CDC. But health officials have emphasized that it’s crucial for people to receive two doses in order to trigger the strongest response from the immune system. Protection against the virus is likely highest two weeks after the second dose, according to the CDC.

The World Health Organization and the CDC have said people at high risk can reduce their chances of exposure to monkeypox by limiting their sexual partners until the second week after they receive the second dose of the vaccine. People can also reduce their risk of exposure by avoiding sex parties until they are vaccinated, according to the CDC.

For people who have monkeypox or whose partners have the virus, the best way to avoid infection is by avoiding sex of any kind while sick, according to the CDC. It’s particularly important to avoid touching any rash and to not share objects or materials such as towels, sex toys, fetish gear or tooth brushes.

The CDC is also encouraging people to exchange contact information with any new sexual partners.